The closest place in the universe where extraterrestrial life might exist is Mars, and human beings are poised to attempt to colonize this planetary neighbor within the next decade. Before that happens, we need to recognize that a very real possibility exists that the first human steps on the Martian surface will lead to a collision between terrestrial life and biota native to Mars.
If the red planet is sterile, a human presence there would create no moral or ethical dilemmas on this front. But if life does exist on Mars, human explorers could easily lead to the extinction of Martian life. As an astronomer who explores these questions in my book Life on Mars: What to Know Before We Go*, I contend that we Earthlings need to understand this scenario and debate the possible outcomes of colonizing our neighboring planet in advance. Maybe missions that would carry humans to Mars need a timeout.